Dobutamine Hydrochloride is a direct-acting inotropic agent whose primary activity results from stimulation of cardiac adrenergic receptors; it produces comparatively mild chronotropic, hypertensive, arrhythmogenic and vasodilatory effects. In contrast with dopamine, it does not release norepinephrine and its actions are not dependent on norepinephrine stores in the heart. In humans, Dobutamine Hydrochloride increases stroke volume and cardiac output and decreases ventricular filling pressure and total systemic and pulmonary vascular resistances.
Drug information sourced from Incepta Pharma.