Allylestrenol is an orally active gestagen. Allylestrenol has a pronounced pregnancy maintaining action in castrated animals without producing hormonal side-effects. In the human, premature termination of pregnancy often follows a fall in the levels of placental hormones. Alestor has been shown to stimulate the placental progesterone production in vitro & to promote the secretion of placental hormones (human chorionic gonadotrophin, human placental lactogen, oestrogens and progesterone) and oxytocinase in patients with pregnancy at risk. In aggrement to this the trophoblastic layers of the placenta show histological signs of activation. Clinical studies have indicated that Alestor is an effective & safe pregnancy preparation. Administration of Alestor in combination with bed rest can remove or prevent the threat of abortion in early pregnancy or stop threatened premature labor.
Drug information sourced from Incepta Pharma.